Shiitake or Hua gu is a type of mushroom and has been used as a food and medicine in China and Japan for thousands of years. It is now cultivated all over the world. The mushroom head is used in herbalism and is combined with another mushroom, known as reishi.
Shiitake contains triterpenoids and glucans (polysaccharides), namely lentinan which has potent immune stimulating and regulating properties. It is also antiviral, anti-cancer, cholesterol lowering and adaptogenic.
Historically it has been used to treat a number of conditions including:
This may be useful at keeping the immune system regulated in people with HIV and may lessen the side effects for anyone undergoing chemotherapy. It is often bought dried and can be used in cooking or as a medicine. It is found in tinctures, capsules, tablets and as an extract called Lentinus Edodes Mycelium (LEM), which is high in active constituents, especially lentinan. Lentinan can be extracted from shiitake but is only available as a drug in Japan, for treatment of cancers and HIV infection. Research suggests that combining lentinan with the HIV antiviral drug - didanosine may be more helpful at fighting the infection - than didanosine alone.
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