herbs - Guggul (Commiphora mukul)

What is it

Guggul, mukul myrrh or gugulipid is a small thorny tree found in India. The stems of the plant contain a yellow resin or gum which has been used in Ayurvedic medicine for many health disorders. 

Action

Guggul contains resin, volatile oils, and gum. Ketone fraction that is extracted from the resin contains potent cholesterol lowering components. This is composed of C21 or C27 steroids, with the major components being Z- and E-Guggulsterone. These compounds also have Antioxidant properties. In addition Guggul appears to reduce the stickiness of the blood.

Uses

The main uses of Guggul are:

• Lowering cholesterol
• Atherosclerosis

Other information

Guggul has very positive action on regulating blood fats, it lowers bad cholesterol (LDL & VLDL) and triglycerides whilst raising good cholesterol levels (HDL). In addition the compounds in Guggul also prevent the build up of arterial plaque by protecting against bad cholesterol oxidation. It is available as tablets or capsules, but is best taken in a standardised extract providing 2.5-5% Guggulsterones.

Cautions

• Generally there are no major side effects standardised Guggul supplements, however some individuals may experience mild digestive discomfort.



• Guggul should be avoided by people with liver diseases, Crohn’s disease, ulcerative colitis and until there is more research on safety, it is best not taken during pregnancy or when breast-feeding. 



• When this article was written there were no well-known negative drug interactions with Guggul supplements.

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