Nephrotic Syndrome
Nephrotic Syndrome is a condition where there is kidney damage which leads to the loss of large amounts of protein in the urine. The loss of protein means that fluid leaks from the capillaries (because there isn't any protein to keep it in) into the tissues, causing swelling, particularly of the feet and the face. The usual underlying cause is damage to the glomeruli as a result of glomerulonephritis, but it can occur in association with other inflammatory conditions such as a vasculitis (inflammaton of blood vessels), or as a side effect of drugs such as penicillamine. Treatment involves bed rest, fluid and salt restriction and diuretics. Some causes may respond to treatment with immunosuppressants.
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